Evolutionary
growth of knowledge and new technological directions of non-thermal plasma
technology in medicine
Mario Coccia National Research Council
of Italy
CNR-CERIS
Institute for Economic
Research on Firm and Growth
Collegio Carlo Alberto -
via Real Collegio, n. 30 10024 Moncalieri (Torino) – ITALY
Georgia Institute of Technology School of Public
Policy 685
Cherry Street, N.W. Atlanta, Georgia, US 30332-0345
Tel.: +39 011 68
24 925;
fax : +39 011 68
24 966; email:
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Ugo Finardi National Research Council
of Italy
CNR-CERIS
Institute for Economic
Research on Firm and Growth Collegio Carlo Alberto -
via Real Collegio, n. 30 10024 Moncalieri (Torino) – ITALY University of Torino
Department of
Chemistry and NIS-Centre of Excellence
via P. Giuria 7, 10125 Torino
Tel.: +39 011 68
24 923;
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24 966; email:
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Abstract:The paper
analyzes the evolution of scientific production and patenting, main proxies of
scientific and technological breakthroughs, concerning non-thermal plasma for
biomedical applications in order to detect emergingtechnological
trajectories. New scientific directions of non-thermal plasma in medicine play
a critical role because they might generate important innovations that could
change the clinical practice. Occurrences of scientific products and patents
are retrieved with Boolean queries on SciVerse database after a meticulous
procedure to delineate the most promising applications in biomedical sciences.
Data are analyzed with two methodological approaches: an exponential model of
growth and regression analysis. Results show high rates of scientific growth
for applications of non-thermal plasma in disinfection, anticancer treatments,
dermatology, whereas for surgery, although values of occurrences are similar to
the other research fields, it shows a different trend that after the 2005 is
decreasing due to the peculiar application to materials for implantation. Some
arguments are discussed at the end of the paper.
Keywords: Non
Thermal Plasma, Technological Trajectories, Plasma, Cancer, Medicine
JEL Codes: O30;
I31
Mario Coccia thanks the
colleagues of the Georgia Institute of Technology for scientific support. In
addition, he gratefully acknowledges financial support from the CNR - National
Research Council of Italy for visiting at Yale University and Georgia Institute
of Technology where this research has been developed. Ugo Finardi acknowledges
the help and spur of Proff. S. Coluccia and L. Battezzati (University of
Torino, Italy). We also thank Ceris-CNR staff and Prof. S. Rolfo of CERIS-CNR
for supporting this research field. We thank an anonymous referee for detailed
comments and suggestions. The usual disclaimer holds, however.